Publications:
Finnson KW, Tam BY, Liu K, Marcoux A, Lepage P, Roy S, Bizet AA, Philip A. Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes. FASEB J. 2006 Jul;20(9):1525-7.
Lerner-Ellis JP, Gradinger AB, Watkins D, Tirone JC, Villeneuve A, Dobson CM, Montpetit A, Lepage P, Gravel RA, Rosenblatt DS. Mutation and biochemical analysis of patients belonging to the cblB complementation class of vitamin B(12)-dependent methylmalonic aciduria. Mol Genet Metab. 2006 Mar;87(3):219-25. Epub 2006 Jan 10.
Sinnett D, Beaulieu P, Belanger H, Lefebvre JF, Langlois S, Theberge MC, Drouin S, Zotti C, Hudson TJ, Labuda D. Detection and characterization of DNA variants in the promoter regions of hundreds of human disease candidate genes. Genomics. 2006 Feb 22.
Lee PD, Ge B, Greenwood CM, Sinnett D, Fortin Y, Brunet S, Fortin A, Takane M, Skamene E, Pastinen T, Hallett M, Hudson TJ, Sladek R. Mapping Cis-Acting Regulatory Variation In Recombinant Congenic Strains. Physiol Genomics. 2006 Jan 31.
Lerner-Ellis JP, Tirone JC, Pawelek PD, Dore C, Atkinson JL, Watkins D, Morel CF, Fujiwara TM, Moras E, Hosack AR, Dunbar GV, Antonicka H, Forgetta V, Dobson CM, Leclerc D, Gravel RA, Shoubridge EA, Coulton JW, Lepage P, Rommens JM, Morgan K, Rosenblatt DS. Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type. Nat Genet. 2006 Jan;38(1):93-100. Epub 2005 Nov 27.
Worgan LC, Niles K, Tirone JC, Hofmann A, Verner A, Sammak A, Kucic T, Lepage P, Rosenblatt DS. Related Articles, Links Spectrum of mutations in mut methylmalonic acidemia and identification of a common Hispanic mutation and haplotype. Hum Mutat. 2006 Jan;27(1):31-43.
Pastinen T, Ge B, Gurd S, Gaudin T, Dore C, Lemire M, Lepage P, Harmsen E, Hudson TJ. Mapping common regulatory variants to human haplotypes. Hum Mol Genet. 2005 Dec 15;14(24):3963-71. Epub 2005 Nov 21.
Ge B, Gurd S, Gaudin T, Dore C, Lepage P, Harmsen E, Hudson TJ, Pastinen T. Related Articles, Links Survey of allelic expression using EST mining. Genome Res. 2005 Nov;15(11):1584-91.
Denarier E, Forghani R, Farhadi HF, Dib S, Dionne N, Friedman HC, Lepage P, Hudson TJ, Drouin R, Peterson A. Related Articles, Links Functional organization of a Schwann cell enhancer. J Neurosci. 2005 Nov 30;25(48):11210-7.
Anderson SK, Dewar K, Goulet ML, Leveque G, Makrigiannis AP. Complete elucidation of a minimal class I MHC natural killer cell receptor haplotype. Genes Immun. 2005 Sep;6(6): 481-92.
Lerner-Ellis JP, Dobson CM, Wai T, Watkins D, Tirone JC, Leclerc D, Dore C, Lepage P, Gravel RA, Rosenblatt DS. Mutations in the MMAA Gene in Patients With the cblA Disorder of Vitamin B(12) Metabolism. Hum Mutat. 2005 Mar;25(3):317.
Croteau S, Roquis D, Charron MC, Frappier D, Yavin D, Loredo-Osti JC, Hudson TJ, Naumova AK. Increased plasticity of genomic imprinting of Dlk1 in brain is due to genetic and epigenetic factors. Mamm Genome. 2005 Feb;16(2):127-35.
Hope Q, Bullock S, Evans C, Meitz J, Hamel N, Edwards SM, Severi G, Dearnaley D, Jhavar S, Southgate C, Falconer A, Dowe A, Muir K, Houlston RS, Engert JC, Roquis D, Sinnett D, Simard J, Heimdal K, Moller P, Maehle L, Badzioch M, Eeles RA, Easton DF, English DR, Southey MC, Hopper JL, Foulkes WD, Giles GG; The Cancer Research UK/British Association of Urological Surgeons’ Section of Oncology Collaborators. Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):397-402.
Lerner-Ellis JP, Dobson CM, Wai T, Watkins D, Tirone JC, Leclerc D, Dore C, Lepage P, Gravel RA, Rosenblatt DS. Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism. Hum Mutat. 2004 Dec;24(6):509-16.
Poon AH, Laprise C, Lemire M, Montpetit A, Sinnett D, Schurr E, Hudson TJ. Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy. Am J Respir Crit Care Med. 2004 Nov 1;170(9):967-73. Epub 2004 Jul 28.
Mira MT, Alcais A, Nguyen VT, Moraes MO, Di Flumeri C, Vu HT, Mai CP, Nguyen TH, Nguyen NB, Pham XK, Sarno EN, Alter A, Montpetit A, Moraes ME, Moraes JR, Dore C, Gallant CJ, Lepage P, Verner A, Van De Vosse E, Hudson TJ, Abel L, Schurr E. Susceptibility to leprosy is associated with PARK2 and PACRG. Nature. 2004 Feb 12;427(6975):636-40. Epub 2004 Jan 25.
Pastinen T, Sladek R, Gurd S, Sammak A, Ge B, Lepage P, Lavergne K, Villeneuve A, Gaudin T, Brandstrom H, Beck A, Verner A, Kingsley J, Harmsen E, Labuda D, Morgan K, Vohl MC, Naumova AK, Sinnett D, Hudson TJ. A survey of genetic and epigenetic variation affecting human gene expression. Physiol Genomics. 2004 Jan 15;16(2):184-93.
Farhadi HF, Lepage P, Forghani R, Friedman HC, Orfali W, Jasmin L, Miller W, Hudson TJ, Peterson AC. Related Articles, Links A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes. J Neurosci. 2003 Nov 12;23(32):10214-23.
J. F. Hilton, K. E. Christensen, D. Watkins, B. A. Raby, Y. Renaud, S. de la Luna, X. Estivill, R. E. MacKenzie, T.J. Hudson & D. Rosenblatt. The Molecular Basis of Glutamamte Formiminotransferase Deficiency Human Mutation (in press).
V. K. Mootha, P. Lepage, K. Miller, J. Bunkenborg, M. Reich, M. Hjerrild, T. Delmonte, A.Villeneuve , R. Sladek, F-H. Zhu, G. A. Mitchell, C. Morin, M. Mann, T.J. Hudson, B. Robinson, J.D. Rioux & E. S. Lander (2003) Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):605-10.
Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Dore C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Despres JP, Gaudet D, Hudson TJ. 5′ flanking variants of resistin are associated with obesity. Diabetes. 2002 May;51(5):1629-34
C.M. Dobson, T. Wai, D. Leclerc, H. Kadir, M. Narang, J.P. Lerner-Ellis, T. J. Hudson, D. S. Rosenblatt & R.A. Gravel (2002). Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria. Human Molecular Genetics. 2002 11(26):3361-3369.
P. Chagnon, J. Michaud, G. Mitchell, J. Mercier, J.F. Marion, E. Drouin, A. Rasquin-Weber, T.J. Hudson & A. Richter (2002). A Missense Mutation (R565W) in Cirhin (FLJ14728) in North American Indian Childhood Cirrhosis (2002) American Journal of Human Genetics. 2002 4;71(6) 1443-14439.
C.M. Dobson, T. Wai, D. Leclerc, A. Wilson, X. Wu, C. Doré, T. J. Hudson, D. S. Rosenblatt & R.A. Gravel (2002). Identification of the gene responsible for the cblA complementation group of vitamin B12 –responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements. PNAS 2002 99(24):15554-15559.
D. Watkins, M. Ru, H.-Y. Hwang, C. D. Kim, A. Murray, N. S. Philip, W. Kim, H. Legakis, T. Wai, J. F. Hilton, B. Ge, C. Doré, A. Hosack, A. Wilson, R. A. Gravel, B. Shane, T. J. Hudson & D. S. Rosenblatt (2002). Hyperhomocysteinemia due to methionine synthase deficiency, (cblG): structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L. American J. of Human Genetics 2002 71(1):143-153.
Mentioned for doing some work:
Thiffault I, Rioux MF, Tetreault M, Jarry J, Loiselle L, Poirier J, Gros-Louis F, Mathieu J, Vanasse M, Rouleau GA, Bouchard JP, Lesage J, Brais B. A new autosomal recessive spastic ataxia associated with frequent white matter changes maps to 2q33-34. Brain. 2006 Sep;129(Pt 9):2332-40.
Marcil M, Vu H, Cui W, Dastani Z, Engert JC, Gaudet D, Castro-Cabezas M, Sniderman AD, Genest J Jr, Cianflone K. Identification of a novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1619-25.
Murdoch S, Djuric U, Mazhar B, Seoud M, Khan R, Kuick R, Bagga R, Kircheisen R, Ao A, Ratti B, Hanash S, Rouleau GA, Slim R. Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Nat Genet. 2006 Mar;38(3):300-2.